Coding
Part:BBa_K3335003:Design
Designed by: TianYu Ma Group: iGEM20_NJU-China (2020-10-21)
We used it to express iRGD-Lamp2b and siRNA targeted at KRAS
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 1277
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
Temporary no.
Source
Sequence is designed by Thermo Fisher. iRGD-Lamp2b sequence is come from Tumor-specific delivery of KRAS siRNA with iRGD-exosomes efficiently inhibits tumor growth.